维生素补充对受污染土壤中的生物可访问性的不同影响,使用多种体外方法及其相关机制
Yi Zhou1, Yongli Zhao1, Peng Xiao1
1College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, PR China; Research Center for Eco-Environment Sciences, Chinese Academy of Sciences, Beijing 100085, PR China.
Ecotoxicology and environmental safety
|July 31, 2024
概括
维生素B1和B6减少了土壤中的胃的生物可获得性,而维生素C增加了它. 这些微量营养素,以及土壤矿物质,显著影响.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 营养科学 营养科学
背景情况:
- (As) 暴露对人类健康构成重大风险.
- 众所周知,像维生素B1,B6和C这样的微量营养素会影响的代谢和毒性.
- 了解土壤中的生物可访问性对于评估健康风险至关重要.
研究的目的:
- 研究维生素B1,B6和C对污染土壤中 (As) 生物可访问性的影响.
- 为了评估这些维生素如何影响在模拟的胃肠道条件下A的溶解.
- 阐明维生素介导的A生物可访问性变化背后的机制.
主要方法:
- 在14个土壤样本上进行了体外生物可访问性测试 (IVG,PBET,SBRC,UBM).
- 添加了维生素B1,B6和C,以评估它们对释放的影响.
- 使用X射线吸收近端光谱 (XANES) 和富里埃变换红外光谱 (FTIR) 进行化学物种分析.
主要成果:
- 维生素B1和B6显著降低了胃A的生物可访问性 (1.14-5.02倍).
- 维生素C增加了胃 (1.13-13.02倍) 和小肠 (1.21-33.35倍) 的生物可访问性.
- 维生素受到As的影响,通过与As和土壤矿物质 (例如Fe (水氧化物) 进行合溶解,而维生素C作为铁的降解剂.
结论:
- 土壤中的矿物质和摄入的维生素极大地影响了胃肠道中的生物可获得性.
- 维生素C可以增强土壤中的释放,可能增加健康风险.
- 这些发现为通过营养干预和风险评估来减轻毒性的策略提供了信息.
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