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新型四基替代5-阿里氨酸皮拉能够干扰血管生成和Ca2+调动

Matteo Lusardi1, Raffaella Belvedere2, Antonello Petrella2

  • 1Department of Pharmacy, Section of Medicinal Chemistry, University of Genoa, Viale Benedetto XV 3, I-16132, Genova, Italy.

European journal of medicinal chemistry
|July 31, 2024
PubMed
概括

新的5-arylamino pyrazoles被合成并测试了抗血管原性质. 化合物2a和2d有效地抑制了内皮细胞管的形成,迁移和入侵,显示出作为抗血管原体的显著潜力.

关键词:
5 - 亚利胺皮拉醇的使用方法血管新生的产生.的恒常化是的恒常化.癌症 癌症 癌症 癌症细胞迁移 细胞迁移内皮管的形成 内皮管的形成

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