饮食蛋白质摄入量与糖尿病病患者死亡率之间的关联
Yichuan Wu1, Jiaqi Chen2, Yuan Tao1
1Department of Endocrinology & Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China; De Feng Academy, Southern Medical University, Guangzhou, China.
饮食中的蛋白质摄入量为1.0-1.2g/kg与糖尿病病患者的死亡率降低有关. 更高的蛋白质摄入量特别有利于60岁及以上的人.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 糖尿病病 (DKD) 是糖尿病的一个主要并发症,增加死亡风险.
- 在DKD患者中,最佳的饮食蛋白质摄入仍然是改善结果的关键研究领域.
研究的目的:
- 检查糖尿病病患者的饮食蛋白质摄入量与全因和心血管死亡率之间的关联.
- 确定特定的蛋白质摄入量水平和来源,这些来源可能会影响该人口的死亡风险.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) 的2901名DKD参与者的数据.
- 将参与者数据链接到国家死亡指数,以获得截至2019年12月31日的死亡结果.
- 在多变量调整后,使用Cox比例危险比率模型来估计危险比率 (HR) 和95%置信区间 (CI).
主要成果:
- 在261,239个人年的随访期间,共有1236人死亡.
- 蛋白质摄入量为1.0-1.2g/kg与所有原因死亡风险降低有关 (HR:0.65;95%CI:0.44,0.96).
- 较高的动物蛋白摄入量与死亡风险增加相关,而较高的蛋白质摄入量有利于老年参与者 (≥60岁).
结论:
- 饮食中的蛋白质摄入量为1.0-1.2g/kg与糖尿病病患者的死亡率降低有关.
- 蛋白质摄入量在0.6-1.2g/kg之间,对60岁及以上的患者显得特别有益.
- 这些发现强调了定制蛋白质建议对于管理DKD死亡风险的重要性.
更多相关视频
04:36Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
Published on: January 12, 2024
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
相关概念视频
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Proteins: Dietary Sources and Requirements
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Psychoneuroimmunology: Diabetes and Cancer
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
