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Updated: Jun 18, 2025

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在B型肝炎疫苗接种后,对抗原特异性T细胞动态的建模表明常规和监管T细胞动态之间的差异

Hajar Besbassi1, George Elias2, Pieter Meysman3

  • 1Centre for Health Economics Research & Modeling Infectious Diseases (CHERMID), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.

Vaccine
|July 31, 2024
PubMed
概括

这项研究模拟了接种疫苗后的T细胞动态,揭示了不同的传统记忆T细胞 (Tconv) 和调节性记忆T细胞 (Treg) 行为. 较早的抗体反应与较慢的T细胞衰变相关,表明改善了疫苗策略.

关键词:
免疫系统的免疫系统.数学模型,混合效应建模.统计 统计 统计 统计T 细胞的动态.疫苗接种 疫苗接种

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