胸部症状和发生心血管疾病的长期风险
Kentaro Ejiri1, Yejin Mok1, Ning Ding2
1Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
The American journal of medicine
|July 31, 2024
概括
胸痛和呼吸困难 (呼吸不全) 与长期心血管疾病风险有关,包括心脏病发作和心力衰竭. 这些症状有助于预测传统风险因素之外的心血管事件.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 早期识别风险因素对于预防心血管疾病至关重要.
- 胸痛和呼吸障碍是常见的症状,可能表明潜在的心血管问题.
研究的目的:
- 调查胸痛和呼吸障碍与发生心血管疾病的长期关联.
- 评估这些症状对特定心血管疾病结果的预测价值,包括冠心病,心力衰竭,心房动和中风.
- 为了确定胸痛和呼吸障碍是否能比已确定的风险因素更好地预测心血管疾病风险.
主要方法:
- 利用了13200名参与社区动脉样硬化风险研究 (1987-1989) 的数据.
- 使用Rose问卷对胸部疼痛进行分类,使用修改后的医学研究委员会尺度对呼吸障碍进行分类.
- 采用多变量Cox模型来评估与事件心血管疾病的关联,平均随访时间约为27年.
主要成果:
- 确定的和可能的胸痛与心肌梗塞和心力衰竭的风险增加显著相关.
- 呼吸障碍 (3-4级) 与心肌梗塞和心力衰竭有显著的关联.
- 胸痛和呼吸障碍改善了整体心血管疾病风险的预测,不包括中风.
结论:
- 胸痛和呼吸困难是长期心血管疾病发病率的独立预测因素.
- 胸痛评估应考虑冠状动脉疾病以外的更广泛的心血管疾病谱.
- 呼吸不良是评估心血管风险的一个重要症状,特别是在心肌梗塞和心力衰竭方面.
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