社会凝聚力作为共同暴露于空气污染和发病痴呆症的修饰因素
Seth Frndak1, Thomas Cudjoe2, Roland J Thorpe3
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, United States of America.
The Science of the total environment
|July 31, 2024
概括
社会凝聚力可以防止痴呆风险. 较高的空气污染暴露仅在社会凝聚力较低的个体中增加了痴呆风险,这表明社会互动起着保护作用.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 社会学 社会学 社会学
背景情况:
- 社会凝聚力与减少压力和提高认知储备有关.
- 空气污染是越来越严重的公共卫生问题,可能会对神经系统疾病产生影响.
- 了解改变空气污染对痴呆症影响的因素对于预防策略至关重要.
研究的目的:
- 调查社会凝聚力对空气污染暴露和发病痴呆症之间的关联的缓和作用.
- 分析社会凝聚力如何影响环境因素与老年人认知衰退之间的关系.
主要方法:
- 队列研究使用来自国家健康和衰老趋势研究 (NHATS) (2011-2018) 的5112名社区成年人 (≥65岁) 的数据.
- 使用美国环保署的社区多层次空气质量建模系统,对五种空气污染物 (PM10,PM2.5,CO,NO,NO2) 的住房人口普查区级暴露量进行了分配.
- 痴呆症状况由NHATS认知查工具和诊断确定;社会凝聚力通过自我评价的邻里信任和帮助力来评估,分为高与低.
- 量子g计算和Cox比例危险模型按社会凝聚力水平分层,以多个共同变量进行调整.
主要成果:
- 无论是高度的社会凝聚力,还是单独暴露于空气污染,都没有与发生痴呆症有显著的关联.
- 较大的联合空气污染暴露与社会凝聚力低的参与者中痴呆风险增加有关 (HR=1.34,95% CI=1.04-1.72).
- 在具有高社会凝聚力的参与者中,没有观察到空气污染和痴呆风险之间的显著关联 (HR=1.00,95% CI=0.93-1.06).
结论:
- 空气污染构成痴呆症的风险,主要是报告邻里社会凝聚力较低的个体.
- 社会凝聚力,可能是通过加强社会互动,可以作为一种保护因素,减轻空气污染对痴呆风险的不利影响.
- 这些发现凸显了社会环境在调节环境暴露对老龄人口认知健康影响方面的重要性.
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