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Updated: Jun 18, 2025

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
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Published on: February 24, 2015

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甲/甲-7,8-二二醇-9,10-氧化物对DNA甲基化的双重作用

Cheng Zhao1, Hui Jin2, Yu Lei1

  • 1Department of Dermatology, The Second Xiangya Hospital of Central South University, Central South University Hunan Key Laboratory of Medical Epigenomics Changsha, China; Research Unit of Key Technologies of Immune-related Skin Diseases Diagnosis and Treatment, Chinese Academy of Medical Sciences Institute of Dermatology, Nanjing, China; Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China; Key Laboratory of Basic and Translational Research on Immune-Mediated Skin Diseases, Chinese Academy of Medical Sciences, Nanjing, China; Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, China; Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha, China.

The Science of the total environment
|July 31, 2024
PubMed
概括

甲 (BaP) 和其代谢物BPDE对DNA甲基化具有双重作用,在高剂量时引起全球低甲基化和关键基因位点的特定高甲基化. 本综述阐明了这些复杂的表观遗传变化,为潜在的治疗见解提供了澄清.

关键词:
自身免疫性疾病是一种自身免疫性疾病.子甲烯乙烯 (Benzopyrene BaP) 是一种子甲-7,8-二二醇-9,10-氧化 (BPDE) 是一种癌症 癌症 癌症 癌症通过DNA甲基化.

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