含有化物和锡功能化的β-TCP纳米粒子的实验牙膏可防止侵蚀性牙磨损
Guilherme Stangler Weiss1, Flávia Rodrigues Oliveira Silva2, Raíssa Manoel Garcia1
1Department of Restorative Dentistry, University of São Paulo (USP), School of Dentistry, Av. Prof Lineu Prestes 2227, São Paulo, SP, 05508-000, Brazil.
Journal of dentistry
|July 31, 2024
概括
含有β-三酸 (β-TCP) 纳米颗粒的牙膏显示出减少牙磨损的潜力,但它们的保护效果与标准化物牙膏相当. 使用化物和锡的功能化并没有提高它们的有效性.
科学领域:
- 生物材料科学 生物材料科学
- 在牙科的纳米技术.
- 牙科材料研究 牙科材料研究
背景情况:
- 牙侵蚀和磨损是对口腔健康的重大关注.
- 制定有效的预防策略对于管理牙磨损至关重要.
- 贝塔三酸 (β-TCP) 纳米颗粒正在探索它们在牙科应用中的潜力.
研究的目的:
- 为了合成包含β-三酸 (β-TCP) 纳米粒子的牙膏.
- 评估这些牙膏在减少侵蚀性牙磨损 (ETW) 的有效性.
- 调查化物和锡功能化对β-TCP纳米粒子功效的影响.
主要方法:
- 牙膏是用化物,锡和β-TCP纳米粒子 (20nm和100nm) 配制的.
- 乳样本经历了侵蚀-磨损循环.
- 使用光学造型测量量量测量了表面损失.
- 评估了牙膏的pH值和可用的化物水平.
主要成果:
- 含有β-TCP纳米颗粒的牙膏证明了对侵蚀-磨损的保护作用.
- 这种保护作用并不优于商业化物牙膏.
- 使用化物和锡的功能化并没有增强β-TCP纳米粒子的保护能力.
- 添加β-TCP减少了实验牙膏中可用的化物的数量.
结论:
- 含有β-TCP纳米颗粒的牙膏对牙侵蚀-磨损提供了一定程度的保护.
- 保护作用与标准的化物牙膏相当.
- 可能需要进一步的研究来优化β-TCP纳米粒子配方,以增强抗侵蚀性质.
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