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疲劳患者中潜在疾病风险:初级保健中的基于人口的队列研究
Becky White1, Nadine Zakkak2, Cristina Renzi3
1Epidemiology of Cancer Healthcare and Outcomes (ECHO) Research Group, Department of Behavioural Science and Health, Institute of Epidemiology & Health Care, University College London, London, UK.
概括
初级保健中新发的疲劳与许多疾病有关,尤其是老年男性的癌症. 本研究量化了这些风险,以帮助疲劳患者的诊断决策.
科学领域:
- 主要护理医学 医疗保健
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 在初级保健中,疲劳表现很常见,但与包括癌症在内的各种疾病有关.
- 疲劳表现后各种诊断的相对概率尚未得到充分确立.
研究的目的:
- 量化新发性疲劳与随后的各种疾病诊断之间的联系.
- 为了具体评估疲劳表现后的癌症风险.
主要方法:
- 一项大型队列研究将新发性疲劳的患者与没有疲劳的患者进行了比较.
- 使用的临床实践研究数据链接数据与医院和癌症登记簿相关联.
- 分析了237种疾病的过度短期发病率,并根据性别和年龄对12个月的风险进行了建模.
主要成果:
- 分析了超过30万患有疲劳的患者和超过40万没有疲劳的患者.
- 疲劳与男性的127种疾病和女性的151种疾病的发病率增加有关,包括抑郁症,感染和甲状腺疾病.
- 到80岁时,癌症在疲劳的男性中是第四高的绝对过度风险 (3.65%的过度),但在女性中不那么突出.
结论:
- 该研究为表现为疲劳的患者提供了诊断的排名概率.
- 研究结果支持优先考虑70岁及以上男性的癌症调查,这些男性表现出疲劳.
- 仅仅是疲劳并不能证明在任何年龄段的女性中优先进行癌症调查.
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