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Updated: Jun 18, 2025

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM
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"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM

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在RAW264巨细胞中,Rit1-TBC1D10B信号调节FcγR介导的细胞形成

Youhei Egami1, Katsuhisa Kawai2, Nobukazu Araki2

  • 1Department of Histology and Cell Biology, School of Medicine, Kagawa University, Miki, Japan egami.yohei@kagawa-u.ac.jp.

Life science alliance
|July 31, 2024
PubMed
概括

Rit1 GTPase和TBC1D10B调节FcγR介导的细胞分裂. 这项研究揭示了它们的信号通路控制着巨细胞中胞体的形成,这对免疫防御病原体至关重要.

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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

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High Throughput Fluorometric Technique for Assessment of Macrophage Phagocytosis and Actin Polymerization09:22

High Throughput Fluorometric Technique for Assessment of Macrophage Phagocytosis and Actin Polymerization

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Immune Surveillance by NK Cells and Phagocytes

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Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
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