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Updated: Jun 18, 2025

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间隙克默序列建模稳定地识别了在进化上遥远的哺乳动物之间保存的调节词汇和远程增强剂

Jin Woo Oh1, Michael A Beer2

  • 1Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA.

Nature communications
|July 31, 2024
PubMed
概括

识别人类和小鼠之间保存的基因调控元素对于疾病研究至关重要. 我们的新算法gkm-align显著提高了这些关键的保护增强剂的发现.

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