结肠直肠癌预后基于饮食模式,使用合成少数群体过量采样技术,使用K-最近邻近方法
S Thanga Prasath1, C Navaneethan2
1School of Computer Science Engineering and Information Systems, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
Scientific reports
|July 31, 2024
概括
每天在面包上食用超过10g的低脂肪黄油会增加结肠直肠癌 (CRC) 的风险. 相反,适度的牛肉,家禽和鱼类摄入量可能会降低CRC风险,突出饮食量.
科学领域:
- 营养流行病学 营养流行病学
- 在瘤学瘤学.
- 数据科学数据科学数据科学
背景情况:
- 结肠直肠癌 (CRC) 是全球癌症死亡的主要原因,饮食是一个重要的贡献因素.
- 了解特定的食物消费模式及其与CRC风险的关联对于公共卫生至关重要.
- 以前的研究表明饮食和CRC之间存在联系,但精确的定量饮食建议仍然是积极研究的领域.
研究的目的:
- 调查特定食品的消费与患结肠直肠癌 (CRC) 的风险之间的关联.
- 评估各种机器学习分类算法在基于饮食数据识别CRC风险方面的性能.
- 提供与CRC风险相关的食品的每日摄入量和每周摄入频率的定量见解.
主要方法:
- 一项前性队列研究,涉及来自美国十个州的15万多名参与者 (男性和女性59岁以上).
- 利用231种食品作为输入特征来识别CRC患者.
- 采用并比较了五种分类算法 (KNN,DT,RF,LRCC,LRLC) 并应用SMOTE算法进行数据平衡.
主要成果:
- 在面包上每天摄入超过10g的低脂肪黄油 (RR 1.99) 和每周两次以上 (RR 1.49) 显著增加CRC风险.
- 每天食用超过74g的牛肉牛排 (RR 0.88) 和每周超过一次 (RR 0.88) 似乎会降低CRC风险.
- 高摄入的家禽 (RR 0.2) 和适度摄入的鱼和猪肉显示出与CRC危险的负相关性.
结论:
- 饮食习惯,特别是消费特定食物的数量和频率,如黄油和牛肉,与结直肠癌 (CRC) 风险有显著联系.
- 机器学习模型在识别与CRC相关的饮食模式方面表现有前途.
- 适度食用牛肉和乳制品,以及更多食用家禽和鱼类,可能有助于降低CRC风险.
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