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Updated: Jun 18, 2025

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening
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SMC3通过调节超级增强剂相关基因,促进心脏发育

Bowen Zhang1, Yongchang Zhu2, Zhen Zhang3

  • 1Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences; ENT Institute, Department of Facial Plastic and Reconstructive Surgery, Eye & ENT Hospital; Institute of Medical Genetics & Genomics; Key Laboratory of Birth Defects, Children's Hospital; Medical Science Data Center at Intelligent Medicine Institute, Fudan University, Shanghai, 200032, China.

Experimental & molecular medicine
|July 31, 2024
PubMed
概括

凝聚素组成部分SMC3的突变通过破坏心脏发育中的基因调节,导致先天性心脏缺陷 (CHD). 这项研究揭示了SMC3.

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