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持续咳患者的长度咳频率监测:每日变化和可预测性
Kian Fan Chung1, Carlos Chaccour2,3,4, Lola Jover5
1National Heart and Lung Institute, Imperial College London, Dovehouse St, London, SW3 6LY, UK. f.chung@imperial.ac.uk.
Lung
|July 31, 2024
概括
持续的咳显示出显著的每日和日复一日的变化. 在30天内测量的咳计数的这种变化需要进一步评估,以便在咳干预中临床使用.
科学领域:
- 肺部病理学 肺部病理学
- 数字健康数字健康
- 生物统计学 生物统计学
背景情况:
- 持续咳是一种常见的疾病,对生活质量产生重大影响.
- 准确可靠的咳频率测量对于评估治疗疗效至关重要.
- 现有的咳监测方法可能很繁,可能无法捕捉每天的波动.
研究的目的:
- 为了确定30天内持续咳的个体的每日咳数量及其变异性.
- 用基于移动应用程序的监测系统来评估咳频率的可预测性.
主要方法:
- 利用Hyfe咳追踪器应用程序,使用手机麦克风和AI算法来监控和识别咳声音.
- 在97名患有持续咳 (≥5次/小时) 30天的个体中分析了每日咳计数和每日可预测率.
- 计算了平均每日咳率,标准偏差和一天可预测性 (ODP),以量化变化和预测准确性.
主要成果:
- 平均每日咳频率差异很大,从每小时6.5到182次咳,有很大的标准偏差.
- 在较高的平均咳率和增加的可变性 (较大的标准偏差) 之间观察到正相关性.
- 总体可预测性反映了30天ODP百分比的平均值,范围从30%到95%,表明咳模式的每天变化很大.
结论:
- 持久咳的个体在30天的咳数量中表现出相当大的一天内和一天到一天的变化.
- 这种观察到的变异性的临床意义需要进一步调查.
- 咳作为咳干预措施的主要终点的实用性需要根据这种变异性进行评估.
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