驾驶一个口内pH值装置来跟踪成年人的胃食道逆流
Shijia Hu1, Clement Wei Ming Lai2, Yu Fan Sim2
1Discipline of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore. denhus@nus.edu.sg.
Scientific reports
|July 31, 2024
概括
与传统的食道方法相比,口内装置为监测胃食道逆流性疾病 (GERD) 提供了更舒适的替代方案. 这种新的方法显示了在GERD诊断和管理中改善患者耐受性的希望.
科学领域:
- 胃肠病学 胃肠病学
- 医疗器械技术 医疗器械技术
- 诊断监测 诊断监测 诊断监测 诊断监测 诊断监测
背景情况:
- 胃食道逆流性疾病 (GERD) 的诊断严重依赖于食道pH值监测,这对患者来说可能是侵入性的和不舒服的.
- 现有的监测方法可能会影响患者的舒适性和坚持,可能会影响诊断准确性和管理策略.
- 需要更少的侵入性和更耐受的GERD监测解决方案.
研究的目的:
- 评估GERD的新型口内pH监测装置的疗效和患者接受度.
- 直接比较口腔内装置与黄金标准的24小时食道pH阻抗监测.
- 评估GERD患者口内pH值监测的舒适性,耐受性和潜在的诊断效用.
主要方法:
- 在十名成年人身上测试了一种具有pH囊在牙保持器中的原型口腔内装置.
- 同时进行24小时食道pH阻抗监测作为黄金标准比较.
- 患者报告的舒适度和日常干扰的结果通过自行管理的调查收集.
主要成果:
- 与食道装置相比,口内装置显示出明显更高的舒适度和较少的干扰日常活动.
- 对口内器械没有报告任何不良事件,而对食道器械发生了一个不良事件.
- 内口装置的准确度在37.82%至86.15%之间,初步发现表明GERD诊断的可能性.
结论:
- 内口pH监测是传统食道监测GERD的更耐受和更舒适的替代方案.
- 这种设备可以作为一种有价值的辅助,用于诊断和持续管理胃食道逆流病.
- 需要进一步的研究来完善准确性,并确定口内pH监测的全部临床实用性.
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