量化营养不良儿童的疾病风险增加:全球元分析和倾向性得分匹配方法
Mukhtar A Ijaiya1, Seun Anjorin2, Olalekan A Uthman3
1Jhpiego, Plot 971, Rueben Okoya Crescent, Off Okonjo Iweala Street, Wuye District, Abuja, FCT, Nigeria. Mukhtarijaiya@yahoo.com.
Global health research and policy
|July 31, 2024
概括
儿童营养不良,特别是消耗和双重营养不良,与儿童发病率的增加有关. 超重儿童的直接风险降低,但可能面临长期问题,需要量身定制的营养策略.
科学领域:
- 全球公共卫生 全球公共卫生
- 儿童营养学 儿童营养学
- 流行病学 流行病学
背景情况:
- 儿童发病率和死亡率仍然是全球重大健康问题.
- 营养不良是各种儿童疾病的关键风险因素,包括呼吸道感染,腹和围产期疾病.
- 了解不同形式的营养不良和儿童发病率之间的联系对于有效的公共卫生干预至关重要.
研究的目的:
- 探索和量化各种形式的儿童营养不良和儿童发病率之间的联系.
- 用自然实验设计估计与营养不良相关的儿童病率的人口归因分数 (PAF).
- 分析与营养不良亚型有关的未调整和调整的发病风险.
主要方法:
- 进行了个人参与者数据 (IPD) 分析.
- 使用倾向得分匹配来创建可比的队列.
- 利用来自27个低收入和中等收入国家的人口和健康调查数据 (2015-2020年).
主要成果:
- 浪费与统计学上显著增加儿童发病风险有关 (RR: 1.094).
- 在初步分析中,双重营养不良显示出非显著的风险增加,但在匹配样本中风险降低 (RR:0.983).
- 超重儿童表现出立即发病风险降低 (RR:0.80在匹配样本中).
结论:
- 儿童消耗和双重营养不良与增加的发病风险有关.
- 儿童超重与较低的立即发病率有关,但需要注意潜在的长期健康后果.
- 细微的,特定于亚型的营养策略对于解决儿童健康结果至关重要.
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