一种健康的植物性饮食可以降低患结直肠癌的风险:病例对照研究
Sazin Yarmand1, Bahram Rashidkhani2, Arezoo Alimohammadi3
1Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Journal of health, population, and nutrition
|July 31, 2024
概括
坚持健康的植物性饮食 (hPDI) 显著降低了伊朗人患结肠直肠癌 (CRC) 的风险. 相反,不健康的植物性饮食 (uPDI) 增加了CRC风险,突出了饮食对预防癌症的重要性.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 结肠直肠癌 (CRC) 在全球范围内是一个重大的健康问题.
- 植物性饮食在CRC风险中的作用在中东人口中未得到充分研究.
- 这项研究通过检查伊朗的植物性饮食模式和CRC风险来弥补这一差距.
研究的目的:
- 研究坚持植物性饮食模式与结直肠癌 (CRC) 风险之间的关联.
- 评估健康 (hPDI) 和不健康 (uPDI) 的植物性饮食指数对CRC风险的影响.
- 提供对中东人口中CRC预防的饮食策略的见解.
主要方法:
- 一项病例控制研究,涉及71名新诊断的CRC患者和142名无癌症的对照在伊朗德黑兰.
- 饮食摄入量使用168项半定量食物频率调查问卷进行评估.
- 使用多变量逻辑回归分析植物性饮食指数 (PDI),不健康植物性饮食指数 (uPDI) 和健康植物性饮食指数 (hPDI).
主要成果:
- 较高的健康植物性饮食指数 (hPDI) 坚持与显著降低CRC风险相关 (OR=0.21;95% CI:0.07-0.56).
- 不健康的植物性饮食指数 (uPDI) 的更大消费显著增加了CRC的风险 (OR=6.76;95% CI:2.41-18.94).
- 总体植物性饮食指数 (PDI) 在调整了混杂因子后,没有显示与CRC风险的显著关联.
结论:
- 更高的健康植物性食品摄入量与降低结直肠癌的风险有关.
- 增加不健康植物性食品的消费与显著增加患CRC的风险有关.
- 饮食选择,特别是健康和不健康的植物成分之间的平衡,在CRC发展中起着至关重要的作用.
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