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Updated: Jun 18, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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激活转录因子3在TP53突变的甲状腺癌细胞中调解了细胞亡和细胞循环停止

Abolfazl Kooti1, Haniyeh Abuei1, Alireza Jaafari2

  • 1Division of Medical Biotechnology, Department of Medical Laboratory Sciences, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Thyroid research
|July 31, 2024
PubMed
概括

过度表达激活转录因子3 (ATF3) 抑制了突变型p53在形甲状腺癌 (ATC) 细胞中的活性. 这表明ATF3是p53-突变甲状腺癌的潜在治疗点.

关键词:
8305C5C8305C5C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8305C8 is the one who is the one who is the one who is the one who is the one who is the one who is the one在ATF3中使用ATF3.突变的 p53 变种在Sharp1中,可以使用Sharp1.这就是TAp63的原因.甲状腺癌是什么?甲状腺癌是什么?的 ΔNp63 的值.

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