赫施普朗格病相关肠球炎:一个系统性审查和元分析
H Poerwosusanta1, Y A Saputra2, A S Budi3
1Lambung Mangkurat University/Ulin Hospital, Faculty of Medicine, Department of Surgery, Paediatric Surgery Division, Banjarmasin, Indonesia. herpoerwo@ulm.ac.id.
The Medical journal of Malaysia
|August 1, 2024
概括
与赫斯普朗氏病相关的肠球炎 (HAEC) 具有重大风险. 手术前的因素,如运动障碍和先天性异常有助于,而便秘和失禁在手术后持续存在.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床研究 临床研究
背景情况:
- 赫施普隆病相关肠球炎 (HAEC) 带来了显著的发病率和死亡率风险.
- 人们对HAEC的病理生理学知之甚少,缺乏有效的治疗策略.
- 目前的研究旨在分析与HAEC相关的术前和术后结果,死亡率和并发症.
研究的目的:
- 分析与HAEC相关的死亡率和并发症.
- 调查影响HAEC的手术前和手术后因素.
- 识别HAEC管理中的持续挑战.
主要方法:
- 按照PRISMA 2020指南进行系统审查.
- 在PubMed和SagePub数据库 (2013-2023) 上进行文献搜索.
- 使用STATA 18进行的元分析.
主要成果:
- 最初的搜索结果显示了370篇PubMed和149篇SagePub文章.
- 过后,有7项研究符合纳入标准.
- 分析重点是从选定的研究中获得的手术前和手术后数据.
结论:
- 手术前的HAEC与肠道运动障碍,便静止和破坏的微生物群有关.
- 主要的先天性异常和低出生体重加剧了手术前的HAEC.
- 在HSCR手术后,便秘和便失禁仍然是手术后的主要挑战.
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