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导向内支气管超声波的跨支气管中支气管冷活检的技术提示,诊断产量和安全性

C I Soo¹, N C Huan², S S Kho³

¹University Malaya Medical Center, University Malaya, Division of Respiratory Medicine, Department of Medicine, Lembah Pantai, Kuala Lumpur, Malaysia. scianray@gmail.com.

The Medical journal of Malaysia

|August 1, 2024

概括

内支气管超声波引导的横支气管中支气管冷活检 (EBUS-TBMC) 为肺癌诊断提供了高的诊断产量和安全性. 这种方法为遗传分析提供了足够的样本,克服了传统EBUS-TBNA的局限性.

科学领域:

肺部病理学肺部病理学
在瘤学瘤学.
干预性肺病学干预性肺病学

背景情况:

胸腔内膜超声导向的跨胸腔针吸收 (EBUS-TBNA) 是肺癌诊断和分期的标准.
来自EBUS-TBNA的细胞学标本可能是小细胞体,特别是在死细胞病变中,影响诊断准确度.
内支气管超声波导向的横支气管中冷活检 (EBUS-TBMC) 正成为获得组织学样本的优越技术.

研究的目的:

评估EBUS-TBMC的诊断产量和安全性.
评估EBUS-TBMC样本在肺癌患者中进行分子检测的充分性.

主要方法:

在马来西亚的高等医疗中心对30名接受EBUS-TBMC治疗的患者进行了回顾性队列研究.
分析程序的成功,并发症率和样本适用于下一代测序 (NGS) 的充分性.

主要成果:

在研究的队列中,EBUS-TBMC表现出高的诊断产量.
该手术表现出良好的安全性,没有报告重大并发症.
所有获得的样本足以通过NGS检测驾驶员的变化.

结论:

EBUS-TBMC是一种安全有效的诊断和分期肺癌的方法.
这种技术为全面的分子分析提供了足够的组织,这对于有针对性的治疗选择至关重要.

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