基于铁的金属有机框架/氧化石墨烯复合电极,用于高效的流量注射电压计检测德克萨米他
Chanida Jakkrawhad1,2, Fonthip Makkliang1,3, Piyaluk Nurerk1,2
1Functional Materials and Nanotechnology Center of Excellence, Walailak University Thasala Nakhon Si Thammarat 80160 Thailand sujittra.po@mail.wu.ac.th.
RSC advances
|August 1, 2024
概括
开发了一种用于检测甲甲 (DEX) 的新型电化学传感器,使用MIL-100(Fe) /石墨烯氧化物复合物改性电极. 这种稳定的传感器在制药和化品样本中提供了灵敏和可重复的DEX量化.
科学领域:
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
背景情况:
- 在制药和化品质量控制中,甲 (DEX) 检测至关重要.
- 现有的分析方法可能缺乏灵敏度,稳定性或成本效益.
- 金属有机框架 (MOF) 和石墨烯氧化物 (GO) 为电化学传感提供了有前途的特性.
研究的目的:
- 开发一种高度稳定的流量注射电压计传感器,用于检测德甲 (DEX).
- 使用笔石墨电极 (PGE) 用MIL-100和石墨烯氧化物 (GO) 复合材料进行修改.
- 在真实样本中评估传感器的性能,稳定性和适用性.
主要方法:
- 制造一个MIL-100(Fe) /GO复合材料修改PGE.
- 使用SEM,EDX,TEM,XRD和FTIR进行表征.
- 通过循环电压测量和安培流量注入分析进行电化学表征.
主要成果:
- 对于DEX检测,MIL-100(Fe) /GO/PGE表现出高效的电子转移.
- 线性检测范围为0.10-5.0 μM和0.010-5.0 mM,低LOD为0.030 μM.
- 传感器表现出卓越的稳定性 (最多55次注射),可重复性,可重复性和抗干扰性能.
结论:
- 开发的电化学传感器为DEX量化提供了灵敏,稳定和可靠的方法.
- 通过在真实制药和化品样本中成功确定,传感器的可行性得到了证实.
- 结果与HPLC-DAD分析有很好的一致性,表明其实际适用性.
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