来自中南中国的肺外结核病的流行病学特征分析
Yanyan Yu1,2, Yu Xiang3,4, Haican Liu3
1Clinical Laboratory, Hunan Provincial Tuberculosis Prevention and Control Institute & Hunan Chest Hospital, Changsha, Hunan, China.
Frontiers in public health
|August 1, 2024
概括
中南中国的肺外结核病 (EPTB) 显示出显著的耐药性 (DR),特别是在肌肉骨结核病中. 这突显了需要改善EPTB的诊断和向治疗.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 肺外结核 (EPTB) 提出了独特的诊断和治疗挑战.
- 了解EPTB的流行病学和耐药性 (DR) 模式对于有效的控制策略至关重要.
研究的目的:
- 调查中国中南部肺外结核病 (EPTB) 的流行病学特征和耐药性模式.
- 为了确定与抗利芬辛/抗多药 (RR/MDR) -EPTB相关的风险因素.
主要方法:
- 在湖南省2013年1月至2021年12月期间,对1324名培养阳性EPTB住院患者进行了回顾性分析.
- 用描述性统计,奇二次测试和后勤回归来分析流行病学和DR数据.
主要成果:
- 淋巴结核病 (29.83%),多重EPTB (20.85%) 和肌肉骨结核病 (14.65%) 是最常见的亚型.
- 总体DR率为25.23%,其中RR/MDR-EPTB为12.39%. 肌肉骨结核病显示了最高的DR率.
- 增加RR/MDR-EPTB的风险与20-59岁的年龄相关,是工人,居住在湖南南部/西部.
结论:
- 湖南省的EPTB表现出显著的耐药性,特别是在肌肉骨结核病中.
- 及时诊断,有效的药物敏感性测试和有针对性的治疗方案对于管理EPTB,特别是肌肉骨形式至关重要.
相关概念视频
Pulmonary Tuberculosis III
316
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
316
Pulmonary Tuberculosis IV
134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis II
215
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
215
Pulmonary Tuberculosis I
228
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
228
Pulmonary Tuberculosis V
176
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
176


