AHA生命的基本8和糖尿病前期/糖尿病之间的关联:一个横截面的NHANES研究
Wei Xu1, Yuntao Feng2, Guzalnur Abdullah1
1Department of Endocrinology and Metabolism, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
Frontiers in endocrinology
|August 1, 2024
概括
基于生活必需8 (LE8) 的较高心血管健康 (CVH) 评分与糖尿病和糖尿病前期风险降低有关. 保持良好的CVH对于预防这些代谢状况至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 美国心脏协会 (AHA) 推出了生命的基本8 (LE8) 来评估心血管健康 (CVH).
- 在LE8定义的CVH与糖尿病前期和糖尿病风险之间的关系需要进一步研究.
研究的目的:
- 评估通过LE8测量的CVH与糖尿病前期和糖尿病发病率之间的关联.
- 确定与葡萄糖代谢障碍最强烈相关的特定CVH成分.
主要方法:
- 从NHANES (2007-2018) 中对7739名美国成年人的横截面分析.
- 使用LE8 (健康行为和因素) 评估CVH.
- 葡萄糖代谢被分为正常,糖尿病前期 (IFG,IGT,IFG+IGT) 和糖尿病;通过逻辑和线性回归分析.
主要成果:
- 在较高的CVH得分和糖尿病前期/糖尿病之间发现了显著的反向关联.
- 最强的反向关联是联合失效的禁食葡萄糖和失效的葡萄糖耐受性 (IFG+IGT) 和CVH.
- 身体质量指数 (BMI) 在非因果途径组件中显示出与糖尿病前期和糖尿病的最强有力的关联.
- 对糖尿病前期的CVH的保护作用在受过高等教育的人群中更为明显.
结论:
- 根据LE8的定义,心血管健康与糖尿病和糖尿病前期风险降低有显著关联.
- LE8为评估与心血管健康相关的代谢健康风险提供了有价值的框架.
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