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腹部和背部的雷肌肉瘤;一个系统的审查
Mari Nanna Øines1, Henry George Smith2, Louise Preisler1,3
1Department of Surgery and Transplantation, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
这一系统性审查强调了诊断和治疗腹腔内和腹腔内肌肉瘤的高质量证据的稀缺性,并强调迫切需要对这些罕见癌症进行更多研究.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
背景情况:
- 腹腔内和腹膜后的雷奥米奥萨科马是一种罕见的恶性瘤.
- 与其他癌症相比,这些瘤存在独特的诊断和治疗挑战.
- 由于严重的发病率和死亡率,迅速和准确的管理至关重要.
研究的目的:
- 系统地审查和综合现有关于非子宫腹部和逆腹膜瘤的诊断和治疗现有证据.
- 识别当前知识和研究中的差距.
主要方法:
- 在PubMed上进行了系统的文献搜索,截至2021年1月.
- 搜索术语包括各种变化"leiomyosarcoma"结合了解剖学位置,如"腹部"和"逆".
- 获取了218项选定的研究的完整文本,最终包括了144项在审查中.
主要成果:
- 该综述确定了144项与非子宫腹部和逆腹膜瘤相关的研究,其中包括非子宫腹部和逆腹膜瘤.
- 观察到大量缺乏高质量的证据,包括随机临床试验.
- 目前对这些罕见瘤的证据基础有限.
结论:
- 需要对腹部和背肌肉菌瘤进行更强大,更高质量的研究.
- 需要更好的证据来优化这些罕见癌症的诊断和治疗策略.
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