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癌细胞被CAR-T细胞向:一个干细胞的问题

Caterina D'Accardo1, Gaetana Porcelli1, Laura Rosa Mangiapane1

  • 1Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.

Frontiers in molecular medicine
|August 1, 2024
PubMed
概括

化学抗原受体 (CAR) -T细胞疗法通过向癌症干细胞 (CSCs) 显示出对固体瘤的承诺. 然而,诸如CAR-T细胞持久性差以及免疫抑制性瘤微环境 (TME) 等挑战限制了疗效.

关键词:
在CAR-T细胞疗法中.抗癌疗法是一种抗癌治疗.癌症干细胞是癌症干细胞.免疫疗法 免疫疗法瘤微环境是一个微环境.

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