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Updated: Jun 18, 2025

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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以化学信息学为基础,对人类癌症的酸化RET氨酸激酶抑制剂进行鉴定

Md Enamul Kabir Talukder1,2, Md Aktaruzzaman1,3, Noimul Hasan Siddiquee1,4

  • 1Laboratory of Computational Biology, Biological Solution Centre, Jashore, Bangladesh.

Frontiers in chemistry
|August 1, 2024
PubMed
概括

研究人员确定了四种新型化合物,其向的是转染过程中重新排列的 (RET) 瘤基因,这是多种癌症的关键驱动因素. 这些化合物显示出抑制RET氨酸激酶活性的潜力,并可能导致新的癌症治疗方法.

关键词:
癌症 癌症 癌症 癌症 癌症验证对接验证对接验证非常精确的对接.高通量虚拟选的高通量虚拟选分子动力学模拟模拟具有一般化的分子力学 出生的表面积.阶段数据库是阶段数据库.在转移氨酸激酶过程中重新排列的酸化.

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