在正常胰腺中,对intravoxel不连贯运动和明显扩散系数参数的可复制性研究
Xiang Liu1, Yi-Feng Wang1, Xiao-Hui Qi1
1Department of CT and MRI, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
胰腺明显扩散系数 (ADC) 值在MRI设备中显示一致性,但intravoxel不连贯运动 (IVIM) 参数表现出中度的重复性,建议在使用IVIM进行胰腺评估时谨慎使用IVIM,因为潜在的机器可变性.
科学领域:
- 放射学 放射学是指放射学
- 医疗成像医学成像
- 量化MRI是指数量化的MRI.
背景情况:
- 在MRI设备之间胰腺明显扩散系数 (ADC) 和内不连贯运动 (IVIM) 参数的一致性对于准确的患者诊断和治疗至关重要.
- 这些定量MRI指标的变化可能会影响临床决策.
研究的目的:
- 为了评估图像质量,ADC值和IVIM参数 (真扩散系数,伪扩散系数, perfusion 分数) 在不同 3.0T MRI 供应商的胰腺检查中的一致性.
- 评估胰腺MRI定量指标的观察者间和设备间协议.
主要方法:
- 对22名健康志愿者使用三家供应商的3.0TMRI进行胰腺扩散权重成像的回顾性分析.
- 主观图像质量评分和ADC和信号噪声比 (SNR) 的定量测量.
- 对IVIM参数计算和使用卡帕测试,ICC,混合线性模型和布兰德-阿尔特曼图表进行统计分析的感兴趣区域 (ROI) 的划分.
主要成果:
- 对主观图像质量 (Kappa = 0.776) 和定量参数 (ICC = 0.803-0.883) 的高度观察者间一致.
- 在不同MRI设备中保持一致的信号噪声比 (SNR) 和明显扩散系数 (ADC) 值 (对于ADC,ICC>0.707).
- 有限的统计学意义上的设备间协议和IVIM参数的一般较低的ICC值,在机器之间观察到D和f值的差异.
结论:
- 表面扩散系数 (ADC) 值显示了胰腺成像的不同MRI设备之间的良好一致性.
- 输入素不连贯运动 (IVIM) 参数的重复性仅适度,显著的变化可能与使用不同的MRI机器有关.
- 胰腺评估的IVIM参数的临床应用需要仔细考虑,因为设备间的变化.
更多相关视频
06:52Stabilized Longitudinal In Vivo Cellular-Level Visualization of the Pancreas in a Murine Model with a Pancreatic Intravital Imaging Window
Published on: May 6, 2021
07:12Author Spotlight: Revolutionizing Pancreatic Disease Understanding Through Advanced Intravital Imaging
Published on: October 6, 2023
相关概念视频
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
Factors Affecting Activity Coefficient
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
Noncompartmental Analysis: Mean Transit, Absorption and Dissolution Time
One of the key parameters is the mean transit time (MTT), which refers to the total duration required for drug molecules to transit through the body. MTT is determined by calculating the ratio of the area under the moment curve to the area...
Noncompartmental Analysis: Miscellaneous Pharmacokinetic Parameters
One key aspect of the noncompartmental approach is determining a drug's total clearance. This can be done by dividing the drug dose by the area under the concentration-time curve from zero to infinity. The area under the concentration-time curve represents the drug's...
