50岁及以上的父亲的社会人口统计趋势和围产期结果
Albert S Ha1, Michael Scott1, Chiyuan Amy Zhang1
1Department of Urology, School of Medicine, Stanford University, Stanford, California.
JAMA network open
|August 1, 2024
概括
在美国,50岁及以上的父亲分娩的百分比正在增加. 这一趋势与使用辅助生殖技术 (ART) 的更高比例,首次孕产妇的出生和不良周产期结果有关.
科学领域:
- 生殖健康 生殖健康
- 父亲的人口统计趋势
- 围产期流行病学 围产期流行病学
背景情况:
- 父亲在分娩时的年龄在全球范围内不断增加.
- 50岁及以上的父亲的社会人口统计数据有限.
- 了解老年父亲的趋势对于公共卫生至关重要.
研究的目的:
- 检查50岁及以上的美国父亲的社会人口统计和时间趋势.
- 调查晚年父亲年龄 (≥50岁) 和围产期结局之间的关联.
主要方法:
- 使用国家生命统计系统 (2011-2022) 进行回顾性横截面研究.
- 包括在研究期间的所有美国出生.
- 对社会人口统计学因素,时间趋势和围产期结果的分析,对母亲因素进行控制.
主要成果:
- 50岁以上的父亲的出生率从1.1% (2011) 增加到1.3% (2022).
- 先进的父亲年龄 (≥50岁) 与辅助生殖技术 (ART) 的使用增加,母亲第一次分娩的比例增加,早产和低出生体重的风险增加有关.
- 在70岁以上和75岁以上的父亲中观察到男性后代的可能性下降.
结论:
- 在美国,涉及老年父亲 (≥50岁) 的分娩比例正在上升.
- 年龄较大的父亲与特定的社会人口统计特征有关,并增加了不良围产期结果和婴儿性别比率变化的风险.
- 进一步的研究和改进的患者咨询是需要这个不断增长的人口.
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