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Updated: Jun 18, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

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通过Ctf18-RFC进行PCNA加载的引导链DNA合成机制

Zuanning Yuan1, Roxana Georgescu2,3, Nina Y Yao2

  • 1Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, USA.

Science (New York, N.Y.)
|August 1, 2024
PubMed
概括

Ctf18-RFC加载器专门将增殖细胞核抗原 (PCNA) 接到 DNA 上,用于领先链DNA聚合酶epsilon (Polε). 这种特异性是通过Ctf18-RFC和Polε之间的独特结构相互作用来实现的.

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