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Updated: Jun 18, 2025

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
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Published on: June 9, 2017

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基于瘤细胞中的ATM/ATR/p53通路,确定与炎症反应相关的分子机制

Chengye Li1, Hanbin Chen2, Xiaojian Chen3

  • 1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, People's Republic of China.

Computers in biology and medicine
|August 1, 2024
PubMed
概括

炎症通过放大活性氧物种 (ROS) 和激活ATM/ATR/p53通路,增加了癌细胞对DNA损伤的敏感性. 这种机制提高了诸如过氧化和紫外线辐射等治疗的有效性.

关键词:
在ATM/ATR/p53路径中.癌症 癌症 癌症 癌症细胞亡是细胞的亡.造成的DNA损伤是DNA损伤.这就是ROSOS ROS.这是一种炎症炎症炎症炎症.

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