在美国中年和老年人群中,生活必需的8个和主要的眼睛疾病之间的关联
Ziling Yang1, Jinming Zhang2, Yajuan Zheng1
1From the Department of Ophthalmology (Z.Y., Y.Z.), The Second Hospital of Jilin University, Jilin University, Changchun, China.
American journal of ophthalmology
|August 1, 2024
概括
通过生命的基本8 (LE8) 评分来衡量心血管健康状况不佳,与患上各种眼睛疾病的风险更高有关. 改善心脏健康可能有助于预防视力丧失.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 心血管健康 (CVH) 和眼部疾病具有共同的风险因素和生物学途径.
- 生命的基本8 (LE8) 算法为评估CVH提供了一个更新的指标.
研究的目的:
- 调查使用LE8算法评估的CVH与主要眼部疾病的患病率之间的关联.
- 探索心血管健康和眼睛健康之间的相关性.
主要方法:
- 一项横截面研究利用了来自国家健康和营养检查调查 (2005-2008) 的40岁及以上的4146名参与者的数据.
- 使用LE8算法评估CVH状态. 通过专业检查来评估眼睛健康.
- 使用加权后勤回归,限制立方线和分层分析来检查LE8得分与眼睛疾病 (包括视网膜病变,白内障,糖尿病视网膜病变和玻璃眼) 之间的关系.
主要成果:
- 较低的LE8得分与任何眼部疾病 (OR:2.03),任何客观确定的眼部疾病 (OR:2.24),视网膜病变 (OR:2.88),糖尿病视网膜病变 (OR:10.23) 和玻璃眼病 (OR:2.76) 的风险增加显著相关.
- 较低的行为子域得分与较高的白内障风险相关 (OR:1.45).
- 亚组分析表明,女性和慢性病患者的LE8和视网膜病变之间存在更强的负相关性.
结论:
- 较低的LE8分数表明,心血管健康状况下降与患眼部疾病的可能性更高有关.
- 促进心血管健康可能是减少眼睛疾病发生率和进展的策略.
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