针对COVID-19后疾病的非侵入性脑刺激:一个系统性审查
Anna Markser1, Jasper Vöckel1, Alexa Schneider1
1University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Cologne, Germany.
The American journal of medicine
|August 1, 2024
概括
非侵入性脑刺激显示出治疗持续性COVID-19后症状的前景. 需要进一步的研究来了解机制,并优化这些治疗方法的长期恢复.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 后COVID-19条件影响全球数百万,呈现多系统性疾病与多种症状.
- 目前COVID-19后的治疗选择有限,这突显了对新型治疗方法的需求.
- 非侵入性和最小侵入性脑刺激技术正在成为潜在的干预措施.
研究的目的:
- 系统地审查目前关于非侵入性或最小侵入性脑刺激对COVID-19后症状有效性的证据.
- 总结使用tVNS,toACS,TMS和tDCS等技术的研究结果.
主要方法:
- 在PubMed/MEDLINE,PsycINFO,Web of Science和Scopus数据库中进行系统的文献搜索.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 由两个独立研究人员进行的经验研究的选择,重点关注COVID-19后患者的大脑刺激.
主要成果:
- 确定了19项研究,包括穿皮漫神经刺激 (tVNS),穿轨交替电流刺激 (toACS),穿磁刺激 (TMS) 和穿直流刺激 (tDCS).
- 这些研究报告了最初有希望的结果,改善了COVID-19后症状的临床结果参数.
- 审查的技术包括tVNS (1项研究),toACS (1项研究),TMS (6项研究) 和tDCS (11项研究).
结论:
- 非侵入性脑刺激技术在缓解COVID-19后症状方面显示出早期的前景.
- 对后COVID-19的更深层次的机制理解以及大脑刺激的精确好处仍然是必要的.
- 未来的研究应该专注于阐明后COVID-19治疗的机制和完善大脑刺激协议.
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