危急疾病中低酸血症的流行病学:一个多中心,回顾性队列研究
Antony George Attokaran1, Kyle C White2, Ra'eesa Doola3
1Intensive Care Unit, Rockhampton Hospital, Rockhampton, Queensland, Australia; University of Queensland, Rural Clinical School, Rockhampton, Queensland, Australia.
Anaesthesia, critical care & pain medicine
|August 1, 2024
概括
低酸盐水平或低酸盐水平在重症监护室 (ICU) 很常见. 中度至重度的低酸血症显著增加了危急病患者90天死亡的风险.
科学领域:
- 关键护理医学 关键护理医学
- 重症监护病房研究 集中护理病房研究
- 电解质不平衡研究研究
背景情况:
- 低酸血是重症患者经常出现的并发症.
- 这项研究调查了澳大利亚ICU中低血症的流行病学和结果.
研究的目的:
- 为了确定ICU患者中低血的发生率和时间.
- 分析低酸血症严重程度与90天病例死亡率之间的关联.
- 检查在ICU之间酸盐替代实践的变化.
主要方法:
- 在澳大利亚昆士兰州的12个ICU进行了回顾性队列研究 (2015-2021).
- 包括68,699名成年人入院ICU,不包括特定的患者群体.
- 分类低血症的严重程度 (无,轻度,中度,严重) 并使用后勤回归进行死亡率分析.
主要成果:
- 34.2%的患者患有低血症,通常是在ICU入院的第二天.
- 酸盐替代策略在ICU之间有很大的差异.
- 90天病例死亡率随着低酸血症严重程度的增加 (轻度:11%,中度:14%,重度:21%).
- 中度和重度的低酸血分别与90天死亡风险增加有关.
结论:
- 低血症在ICU中很普遍,通常在早期出现并在几天内纠正.
- 在酸盐管理协议中存在显著的变化.
- 中度至重度的低酸血是危重病患者死亡率增加的重要危险因素.
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