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结合基于结构的虚拟查和机器学习方法,用于识别潜在的ACC和DGAT2双重抑制剂

Liangying Deng1, Yanfeng Liu2, Nana Mi3

  • 1Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China; Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing 211200, China.

International journal of biological macromolecules
|August 1, 2024
PubMed
概括

研究人员确定了对乙-协酶A碳氧化酶 (ACC) 和二甲糖醇乙转移酶2 (DGAT2) 的潜在双重抑制剂,用于治疗非酒精性脂肪肝疾病 (NAFLD). 这项计算研究通过同时针对ACC和DGAT2,为NAFLD提供了新的治疗策略.

关键词:
乙烯基共酶A 碳酸酶甲基糖酸转移酶2的二甲基糖.双重抑制剂 双重抑制剂机器学习 机器学习虚拟选是一个虚拟的选.

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