胎儿异常对母亲的影响:基于人口的横截面研究
Rula Atwani1, Michael Aziz2, George Saade1
1Department of Obstetrics and Gynecology, Macon and Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA (Atwani, Saade, Kawakita).
American journal of obstetrics & gynecology MFM
|August 1, 2024
概括
孕产妇的健康风险随着胎儿异常增加,严重孕产妇发病率 (SMM) 风险因异常类型而异. 对这些风险的咨询对于做出明智的怀孕决定至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 众所周知,胎儿异常会增加母亲患病风险.
- 与不同类型的胎儿异常相关的具体风险仍然定义不佳.
研究的目的:
- 调查与特定的胎儿异常类型有关的不良母亲健康结果.
- 根据胎儿异常分类来量化严重孕产妇发病率 (SMM) 的风险.
主要方法:
- 对美国生命统计数据的分析 2011-2020年活产/婴儿死亡数据.
- 包括怀孕20周或更长的怀孕.
- 定义SMM是ICU入院,输血,子宫破裂或子宫切除.
- 在具有特定胎儿异常的怀孕和没有特殊胎儿异常的怀孕中,SMM风险的比较.
- 使用调整后的相对风险 (aRR) 的修改后的波桑回归和调整后的风险差异 (aRDs) 的边际标准化.
主要成果:
- 所有分析的胎儿异常,除了胃和四肢异常,都与增加SMM风险有关.
- 无脑症和脑瘤显示SMM的相对风险增加最高.
- 在大多数胎儿异常类型中观察到SMM的绝对风险增加,无脑症和脑显示出最大的差异.
结论:
- 胎儿异常与不利的孕产妇健康结果显著相关,包括严重的孕产妇发病率.
- SMM风险的程度取决于特定类型的胎儿异常.
- 告知母亲关于胎儿异常对母亲健康的潜在影响,对于怀孕管理的共同决策至关重要.
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