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阻断葡萄糖-6-酸盐脱酶会诱导免疫细胞死亡,并加速免疫疗法

Motoki Nakamura1, Tetsuya Magara2, Maki Yoshimitsu2

  • 1Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Japan motoki1@med.nagoya-cu.ac.jp.

Journal for immunotherapy of cancer
|August 1, 2024
PubMed
概括

抑制葡萄糖-6-酸脱酶 (G6PD) 触发癌细胞死亡,增强瘤免疫力,改善对ICI等免疫疗法的反应.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂免疫治疗是一种免疫疗法.黑色素瘤是一种黑色素瘤.非小细胞肺癌非小细胞肺癌

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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