开发和验证用于药物服药应用的移动服药满意度表 (MASS)
Rajat Rana1, Baharudin Bin Ibrahim1, Hasniza Binti Zaman Huri1
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Research in social & administrative pharmacy : RSAP
|August 1, 2024
概括
移动坚持满意度表 (MASS) 是为了测量用户对药物坚持的mHealth应用程序的满意度而开发的. 积极的用户界面和功能对于持续的参与和坚持至关重要.
科学领域:
- 医疗信息学 医疗信息学
- 患者坚持的研究研究.
- 移动健康 (mHealth) 技术评估
背景情况:
- 药物不服药是治疗慢性疾病的一个重大挑战.
- 移动健康 (mHealth) 应用程序为改善药物坚持提供了一个有希望的途径.
- 评估用户对mHealth应用程序的满意度的现有工具是有限的.
研究的目的:
- 开发和验证移动坚持满意度表 (MASS).
- 评估用户对旨在提高药物服药能力的mHealth应用程序的满意度.
- 确定影响用户满意度的关键因素在mHealth遵守工具中.
主要方法:
- 一种混合方法的方法,涉及文献审查,专家咨询和患者采访.
- 使用双轮Delphi技术开发MASS,然后进行试点测试.
- 验证26项,六维MASS与135名成年患者使用探索性和确认性因子分析.
主要成果:
- MASS显示出高可靠性和有效性,Cronbach的α>0.70在所有维度.
- 探索和确认因素分析支持MASS的六维结构.
- 用户界面和功能满意度对整体满意度产生了显著的积极影响,解释了23.1%的差异.
结论:
- MASS是一个可靠和有效的工具,用于评估用户对mHealth遵守应用程序的满意度.
- 优化mHealth应用程序的用户界面和功能对于促进长期用户参与至关重要.
- 通过深思熟虑的设计来提高用户满意度,可以有助于更好的药物坚持结果.
相关概念视频
01:10In Vitro Drug Release Testing: Overview, Development and Validation
593
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
593
01:14Drug Dissolution: Requirements and Profile Comparison
500
The acceptance criteria for dissolution profile data are anchored in Q values, representing the percentage of drug dissolved within a specified period. This assessment unfolds in three stages:First Stage: The test passes if all six drug dosage units are equal to or greater than Q plus 5%; otherwise, the sample proceeds to the second stage.Second Stage: The average of twelve units must be equal to or greater than Q, with no unit falling below Q - 15% to pass; if not, it progresses to the final...
500
01:20Drug Product Performance: In Vitro–In Vivo Correlation
431
In pharmaceutical development, it's crucial to establish a predictive in vitro–in vivo correlation (IVIVC) for two or more formulations to gain a comprehensive understanding of release properties. IVIVC reduces the need for costly in vivo studies and facilitates the establishment of meaningful dissolution specifications with significant cost savings and decreased regulatory burden. Furthermore, a meaningful IVIVC should predict Cmax and AUC within 20%, aligning with FDA guidance while...
431
01:29Clinically Relevant Drug Product Specifications: Methods of Establishment
300
Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
300
01:16Therapeutic Drug Monitoring: Overview and Classification
642
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
642
01:26Therapeutic Drug Monitoring: Drug Analysis Methods
342
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
342