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Updated: Jun 18, 2025

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在侵袭性NK/T细胞新生瘤中CD6的表达和评估作为潜在的治疗点:骨髓病理研究小组研究

Xiaoxian Zhao1, Chad M McCall2, Jared G Block2

  • 1Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC; Department of Laboratory Medicine, Cleveland Clinic, Cleveland OH.

Clinical lymphoma, myeloma & leukemia
|August 1, 2024
PubMed
概括

CD6在最具侵略性的NK/T细胞瘤中表达,如ANKLL和ENKTL. 在临床前模型中,一种CD6抗体-药物结合体显示出有前途的结果,表明CD6是潜在的治疗标.

关键词:
ANKL 模型模型侵袭性的NK细胞白血病/淋巴瘤 (ANKLL)在CD6 CD6 CD6 CD6 CD6 CD6 CD6这就是CD6-ADC.额外的NK/T细胞淋巴瘤 (ENKTL)

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Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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