使用行政索赔数据,对冠状病毒病2019年相关肺阿斯伯吉洛症的发生率和危险因素
Waki Imoto1,2,3,4,5, Yasutaka Ihara6,7, Takumi Imai6
1Department of Infection Control Science, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
在日本,COVID-19相关的肺阿斯伯吉洛症 (CAPA) 影响了0.4%-2.7%的严重COVID-19患者. CAPA与死亡率增加有关,年龄和免疫抑制剂等因素增加了风险.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 与COVID-19相关的肺炎 (CAPA) 是COVID-19的一种严重并发症,发生率可变.
- 在日本,关于CAPA的发病率,风险因素和死亡率的研究有限.
研究的目的:
- 在日本的严重或危急的COVID-19患者中调查CAPA的发病率和危险因素.
- 为了评估CAPA和这个患者队列中的死亡率之间的关联.
主要方法:
- 利用来自日本急症护理医院的行政索赔数据,用于一组严重至危急的COVID-19患者.
- 采用多变量回归模型来确定CAPA的风险因素及其对死亡率的影响.
主要成果:
- 在33136名患者中,CAPA的发病率从0.4%到2.7%不等.
- 确定的危险因素包括晚年,男性性别,慢性肺病,类固醇/免疫抑制剂使用,ICU入院,输血和透析.
- CAPA被确定为死亡率的独立预测指标.
结论:
- 在严重和危急的COVID-19病例中,CAPA代表了一个严重的并发症.
- 在这些患者中,CAPA的存在与死亡风险增加有关.
更多相关视频
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
08:01Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
相关概念视频
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pneumonia III: Complications and Assessment
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
