甘油三糖指数与胆结石之间的关联:一个横截面研究
Hongliang Li1, Congfeng Zhang2
1Department of General Surgery, Dandong Central Hospital, Dandong, China.
Scientific reports
|August 1, 2024
概括
甘油三糖 (TyG) 指数与较高的胆结石风险有关. 这一发现表明,TyG指数可以预测胆结石的发展,特别是在特定的人口群体.
科学领域:
- 代谢综合征研究 代谢综合征研究
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 胆结石是一种常见的胃肠道疾病.
- 甘油三糖 (TyG) 指数正在成为代谢功能障碍的标志物.
- 了解胆结石形成的预测因素对于公共卫生至关重要.
研究的目的:
- 调查甘油三糖指数 (TyG) 与胆结石患病率之间的关联.
- 根据TyG指数水平,确定患胆结石风险较高的子组.
主要方法:
- 利用了2017-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 包括3870名20岁以上的参与者.
- 使用后勤回归,子组分析和平滑曲线拟合来分析关系.
主要成果:
- 在研究人群中观察到胆结石的发病率为10.4%.
- 泰格指数的每一个单位增加都与胆结石风险增加41%有关 (OR 1.41).
- 通过平滑的曲线拟合证实了正相关性,并观察到子组,包括女性,50岁以下的人和BMI>25的个体.
结论:
- 甘油三糖 (TyG) 指数与胆结石风险正相关.
- TyG指数作为胆结石发展的潜在预测标记.
- 针对性干预可能对Tyg指数水平较高的个体有益.
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