相关实验视频
Updated: Jun 18, 2025

07:48
Working with Human Tissues for Translational Cancer Research
Published on: November 26, 2015
9.9K
答案ALS返回结果的研究:回答披露义务
Jennifer Roggenbuck1, Mackenzie Kaschalk1, Rory Eustace1
1Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Amyotrophic lateral sclerosis & frontotemporal degeneration
|August 2, 2024
概括
答案返回ALS结果 (RoAR) 研究成功地与参与者分享了基因测试结果. 该模型通过提供对其遗传信息的访问来赋予研究参与者权力,改善未来的基因组项目设计.
科学领域:
- 基因组学就是基因组学.
- 神经科学是一个神经科学.
- 遗传研究 遗传研究
背景情况:
- 答案ALS研究是一项大型,前性的自然历史和生物存储库倡议.
- 参与者最初没有提供接受遗传检测结果的选择.
研究的目的:
- 建立一个机制,与参与者共享选择的临床遗传测试结果的回答ALS研究.
- 评估参与者与遗传结果披露的经验.
主要方法:
- 在RoAR研究中,参与者同意接受5个特定的ALS基因和/或59个医学可操作基因的结果.
- 患者报告的基因测试结果是通过后披露调查收集的.
主要成果:
- 在645名符合条件的参与者中,有143人 (22%) 完成了RoAR研究.
- 在15.4%的参与者中发现了致病变体 (13%在ALS基因中,6.3%在ACMG基因中).
- 参与者报告的研究结果披露的实用性与临床环境的实用性相当或超过.
结论:
- RoAR研究为基因组研究中的"披露研究"提供了一个成功的模型.
- 结果可以为未来的大规模基因组项目设计提供信息,以加强参与者参与和数据访问.
相关概念视频
Obedience
32.8K
According to obedience research, we may harm others under the forceful pressures of an authority figure (Milgram, 1974). How about if the inappropriate orders were delivered with less force? The increasing interdependence between nurses and physicians compelled Hofling and his colleagues to explore nurses’ reactions to a potentially harmful medical request made by the perceived authority figure, the doctor (Hofling, Brotzman, Dalrymple, Graves, & Pierce, 1966). In this situation,...
32.8K
Ethics and Bioethics
1.3K
Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
1.3K
Ethical Standards II
655
Ethical standards are the backbone of nursing practice, guiding nurses as they interact with patients, families, and colleagues. These standards are crucial for providing safe, empathetic care centered on the patient's needs.
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
Confidentiality is crucial, embodying respect for individual privacy...
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
Confidentiality is crucial, embodying respect for individual privacy...
655
Ethical Standards I
789
The American Nurses Association (ANA) created and implemented the first nationally accepted Code of Ethics for Nurses with Interpretive Statements. The Code of Ethics is a living document regularly updated by the ANA and establishes an ethical standard that is non-negotiable for nurses in all roles and settings.
The Code of Ethics provisions outline the nurse's duty to the patient, the healthcare team, the profession, and society. The Code's fundamental principles include advocacy,...
The Code of Ethics provisions outline the nurse's duty to the patient, the healthcare team, the profession, and society. The Code's fundamental principles include advocacy,...
789
Accountability and Responsibility of a Nurse II
679
Professional accountability in nursing is a multifaceted concept that encompasses professional ethics, legal standards, and employment expectations. This framework ensures that nurses maintain and elevate the quality of care while upholding the values of their profession. It compels them to treat patients, families, and colleagues with respect, compassion, and integrity.
For example, a nurse demonstrating respect and compassion might listen attentively to a patient's concerns, provide...
For example, a nurse demonstrating respect and compassion might listen attentively to a patient's concerns, provide...
679
Nurses' Legal Responsibilities II
694
Establishing a secure, collaborative nurse-patient relationship is crucial for delivering high-quality care. This relationship, founded on trust, respect, and honesty, enhances the patient's comfort and willingness to share vital health information. For example, a nurse who listens actively and without judgment provides clear information about health conditions and treatment options and respects patient decisions, which builds a trusting relationship.
Communication between nurses and...
Communication between nurses and...
694

