最近在被诊断为直肠癌的患者中,癌症特异性死亡率的种族/民族差异
Lu Li1,2, Zhenpeng Xu1,3, Guanghua Chen2
1Department of Colorectal Surgery, Jiangsu Province Hospital of Chinese Medicine, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Translational gastroenterology and hepatology
|August 2, 2024
概括
结直肠癌死亡率的种族差异仍然存在,特别是在黑人患者中,即使考虑到临床因素和治疗. 解决医疗保健不平等问题对于减少这些生存结果差距至关重要.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
- 健康差异 在健康上的差异
背景情况:
- 非洲裔美国患者经常接受低于最佳的直肠癌治疗,与白人患者相比,其生存结果较差.
- 结直肠癌死亡率的种族和民族差异是一个重大的公共卫生问题.
- 了解导致这些差异的因素对于改善患者护理至关重要.
研究的目的:
- 分析直肠癌特定死亡率的种族和民族差异.
- 为了确定这些差异是否在调整临床特征,治疗和获得护理的因素后仍然存在.
主要方法:
- 利用了2011年至2020年间被诊断患有直肠癌的个人监测,流行病学和最终结果数据库.
- 计算了直肠癌特异性死亡率的累积发病率.
- 采用了Fine和Gray回归模型来估计分分布危险比率 (sdHRs),并逐步调整.
主要成果:
- 非西班牙裔黑人患者的直肠癌特异性死亡率累计发病率最高 (39%).
- 与NH-White患者相比,NH-Black患者的死亡风险增加了28%,即使在临床调整后.
- 在调整后,西班牙裔,美洲印第安人/阿拉斯加原住民和亚洲/太平洋岛民群体的差异并不显著.
结论:
- 结直肠癌死亡率的种族/民族差异受到临床特征,治疗和获得护理的差异的影响.
- 在结直肠癌中观察到的黑人-白人死亡率差距在考虑这些因素后仍然存在.
- 公平的医疗保健对于减轻直肠癌结果的种族/民族差异至关重要.
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