老年人营养风险指数对于脑的老年患者的康复结果具有预后价值
Xu Pei1, Yutu Zhang2, Dongfeng Jiang3
1Department of Critical Care Medicine and Neurosurgery of Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.
Frontiers in nutrition
|August 2, 2024
概括
近一半的老年脑患者面临营养不良的风险. 老年营养风险指数 (GNRI) 有效地预测了康复结果,有助于为这个脆弱人群进行临床干预.
科学领域:
- 老年医学 老年医学
- 神经学 神经学
- 营养科学 营养科学
背景情况:
- 老年营养风险指数 (GNRI) 是一种验证的工具,用于评估老年人营养状况和预后.
- 老年人脑缺少关于营养风险及其对结果的影响的足够研究.
- 这项研究通过调查老年脑患者的营养风险患病率和预后价值来弥补这一差距.
研究的目的:
- 为了确定使用GNRI在脑的老年患者中营养风险的患病率.
- 评估GNRI对该患者群体临床结果的预后意义.
- 探索GNRI与炎症和并发症的临床指标之间的相关性.
主要方法:
- 一项前性队列研究,涉及100名被诊断患有脑的老年患者.
- 数据收集包括人口和临床特征,GNRI计算和格拉斯哥结局量表 (GOS) 评估在出院6个月后.
- 统计分析包括相关性和多变量后勤回归来评估GNRI的预测价值.
主要成果:
- 48%的患者表现出基于GNRI的营养不良风险.
- 营养不良患者的C反应性蛋白 (CRP) 水平较高,并发病率更多,年龄调整后查尔森并发病率指数 (aCCI) 得分更高.
- 较低的GNRI得分与较差的GOS结果显著相关 (OR=0.826,p<0.001),GNRI值为97.50预测恢复不良,具有高灵敏度和特异性.
结论:
- 患有脑的老年患者存在营养不良的高风险.
- GNRI是预测老年脑患者康复的有价值的预后工具.
- GNRI可以指导临床干预和康复策略,以改善患者的治疗结果.
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