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Updated: Jun 18, 2025

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
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Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine

Published on: May 21, 2012

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Prdm16依赖的抗原呈现细胞诱导对肠道抗原的耐受性

Liuhui Fu1, Rabi Upadhyay1,2, Maria Pokrovskii1,3

  • 1Department of Cell Biology, New York University School of Medicine, New York, NY, USA.

bioRxiv : the preprint server for biology
|August 2, 2024
PubMed
概括

研究人员通过编程调节性T细胞 (Tregs) 来识别了对口服耐受性至关重要的宽容性树突细胞 (tDCs). 这些细胞对于管理对食物和肠道微生物的免疫反应至关重要,为过敏和自身免疫性疾病提供治疗潜力.

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Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells06:57

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The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
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Renewal of Intestinal Stem Cells01:23

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Antigen Presenting Cells

The immune system is a complex network of cells and molecules that protects the body from foreign invaders. T cells, a type of white blood cell, play a crucial role in this process. They recognize and attack foreign substances, such as pathogens, that enter the body.
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Complete Antigens
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T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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