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Updated: Jun 18, 2025

Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in Cultured Human Cells
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Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in Cultured Human Cells

Published on: August 12, 2015

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G四重复体是BRCA2缺陷颗粒细胞原始体和脑髓母细胞瘤的脆弱性来源

Danielle L Keahi1, Mathijs A Sanders2,3, Matthew R Paul4

  • 1Laboratory of Genome Maintenance, The Rockefeller University, New York, NY, USA.

bioRxiv : the preprint server for biology
|August 2, 2024
PubMed
概括

大脑小细胞中的BRCA2缺乏会在G-四重复中造成DNA损伤,导致脑髓母细胞瘤. 在瘤中PIF1基酶的升级表明它存在.

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