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Updated: Jun 18, 2025

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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在非正规部位的Pin1催化普罗林cis-trans异构的基础上存在一种连接机制

Christopher C Williams1,2, Jonathan Chuck1,2, Paola Munoz-Tello3

  • 1Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, United States.

bioRxiv : the preprint server for biology
|August 2, 2024
PubMed
概括

在PPARγ核受体中,prolyl异构酶Pin1酶结合并异构化普罗林键. Pin1使用连接机制来催化非正规部位的异体化,揭示了一个精细的催化模型.

关键词:
生物科学 生物科学生物物理和计算生物学核磁共振光谱法 (NMR) 是一种光谱法.在PPARγ中,PPARγ是PPARγ一个Pin1一个Pin1这是一种 cis-trans 异构化.酵素酶是一种酶.核受体是核受体的一个组成部分.氨酸的异构化

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