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Updated: Jun 18, 2025

Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients

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系统的多omics调查的雄激素受体驱动的基因表达和表观遗传学变化在前列腺癌

Lin Li1,2, Kyung Hyun Cho1, Xiuping Yu1,2,3

  • 1Department of Biochemistry and Molecular biology, LSU Health Shreveport, Shreveport, LA.

bioRxiv : the preprint server for biology
|August 2, 2024
PubMed
概括

这项研究使用多omics数据分析了前列腺癌中的雄激素受体 (AR) 信号. 抗雄激素剥夺疗法改变了基因表达和AR结合部位,揭示了前列腺癌进展的见解.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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