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Updated: Jun 18, 2025

Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay
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Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay

Published on: July 28, 2014

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Gz增强信号转导试验 (GZESTY) 用于GPCR脱化

Luca Franchini1, Joseph J Porter1, John D Lueck1

  • 1Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA.

bioRxiv : the preprint server for biology
|August 2, 2024
PubMed
概括

我们开发了GZESTY,这是一种基于细胞的敏感测试,用于研究与Gi/o/z蛋白结合的G蛋白结合受体 (GPCR). 这种测定有助于识别孤儿GPCRs的配体,并了解它们的功能.

关键词:
G蛋白结合受体 (GPCR) 是一种受体.基于细胞的测定.高通量选的高通量选分子药理学分子药理学孤儿GPCRR的使用情况

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