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Updated: Jun 18, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
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帕内拉:一种创新的框架,用于克服微生物社区建模中的不确定性,使用泛基纳代谢模型

Indumathi Palanikumar1,2,3, Himanshu Sinha1,2,3, Karthik Raman1,2,3,4

  • 1Department of Biotechnology, Bhupat Jyoti Mehta School of Biosciences, Indian Institute of Technology (IIT) Madras, Chennai 600 036, India.

iScience
|August 2, 2024
PubMed
概括

帕内拉模型微生物群落使用泛属代谢模型 (PGMMs) 克服16S rRNA数据限制. 这种方法增强了代谢推理,并减少了社区建模中的错误.

关键词:
生物信息学是一种生物信息学.计算生物信息学是指计算机生物信息学.微生物学 微生物学系统生物学 系统生物学

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Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
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