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Updated: Jun 18, 2025

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经过光遗传修饰的人类胚胎干细胞衍生的视神经元与耳细胞核建立了功能性突触连接.

Yanni Chen1,2,3,4, Wenbo Mu1,2,3,4, Yongkang Wu5

  • 1Institute of Translational Medicine, and Children's Hospital Affiliated and Key Laboratory of Diagnosis and Treatment of Neonatal Diseases of Zhejiang Province, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.

Journal of tissue engineering
|August 2, 2024
PubMed
概括

人类胚胎干细胞 (hESCs) 被转化为耳神经元 (ONs),用于治疗聋. 这些干细胞衍生的眼神经元 (eON) 成功形成了功能连接,为螺旋质神经元 (SGN) 损伤提供了潜在的治疗方法.

关键词:
听觉的电路是听觉的.神经再生是一种神经再生.视觉遗传学 视觉遗传学器官类型的培养.眼神经元 眼神经元

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